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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
38.48
Human Site:
Y399
Identified Species:
76.97
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
Y399
R
V
L
W
K
F
Q
Y
I
L
N
P
R
Q
V
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
F309
P
E
I
G
L
R
L
F
K
D
V
P
D
S
R
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
Y399
R
V
L
W
K
F
Q
Y
I
L
N
P
R
Q
V
Dog
Lupus familis
XP_531626
735
82556
Y399
R
V
L
W
K
F
Q
Y
L
L
N
P
R
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
Y395
S
V
L
W
K
F
Q
Y
I
L
N
P
R
Q
V
Rat
Rattus norvegicus
P51556
727
82180
Y392
S
V
L
W
K
F
Q
Y
I
L
N
P
R
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
Y459
R
I
Y
R
K
F
Q
Y
L
L
N
P
R
Q
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
Y403
R
V
L
R
K
F
Q
Y
L
L
N
P
R
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
Y575
R
I
L
R
K
F
Q
Y
M
L
N
P
R
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
Y450
K
I
L
Q
K
F
E
Y
L
L
N
P
R
Q
V
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
Y892
R
I
M
R
K
F
Q
Y
L
L
N
P
R
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L384
S
L
R
Q
R
L
H
L
H
L
N
P
V
Q
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
86.6
N.A.
80
N.A.
66.6
73.3
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
93.3
N.A.
93.3
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
84
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
34
9
0
0
0
0
0
34
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
84
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
9
67
0
9
9
9
9
42
92
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
17
0
0
75
0
0
0
0
0
0
92
0
% Q
% Arg:
59
0
9
34
9
9
0
0
0
0
0
0
84
0
9
% R
% Ser:
25
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
50
0
0
0
0
0
0
0
0
9
0
9
0
92
% V
% Trp:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _